The Buzsaki Lab is proud to present a large selection of experimental data available for public access. We publicly share more than a thousand sessions (about 40TB of raw and spike- and LFP-processed data) via our public data repository. The datasets are from freely moving rodents and include sleep-task-sleep sessions (3 to 24 hrs continuous recording sessions) in various brain structures, including metadata. We are happy to assist you to use these data. Our goal is that by sharing these data, other users can provide new insights, extend (or contradict/clarify) our conclusions.
The database contains electrophysiological recordings performed in freely moving rats and mice collected by investigators in the Buzsaki Lab over several years (a subset from head-fixed mice). Sessions has been collected with extracellular electrodes using high-channel-count silicon probes, with spike sorted single units, and intracellular and juxtacellular combined with extracellular electrodes. Several sessions include physiologically and optogenetically identified units. The sessions have been collected from various brain region pairs: the hippocampus, thalamus, amygdala, post-subiculum, septal region and the entorhinal cortex and various neocortical regions. In most behavioral tasks, the animals performed spatial behaviors (linear mazes and open fields), preceded and followed by long sleep sessions. Brain state classification is provided.
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Series Combats Disorders: First Up, Epilepsy People with epilepsy were once thought to be possessed by demons or evil spirits. Dubbed “the sacred disease,” epilepsy [...]
Poster session at SfN in San Diego, 2018
Attendance of Buzsaki lab poster session at SFN2018 San Diego, Wednesday, 4 PM.
Optogenetics/Brain Research: Optical developments take optogenetics deeper, less invasively
Optogenetics has rocked the world of neuroscience for more than a decade now. But neuroscientists want more from the technique—and less, including more depth and less invasiveness. As [...]
The Time Debate: The Neurons That Tell Time
In June of 2007, Albert Tsao, a nineteen-year-old native of Silver Spring, Maryland, was working in Trondheim, Norway, at the Kavli Institute for Systems Neuroscience. Tsao was a [...]
Transformation of a Spatial Map across the Hippocampal-Lateral Septal Circuit
The hippocampus constructs a map of the environment. How this “cognitive map” is utilized by other brain regions to guide behavior remains unexplored. To examine how neuronal firing patterns in [...]
Cocaine Place Conditioning Strengthens Location-Specific Hippocampal Coupling to the Nucleus Accumbens
Conditioned place preference (CPP) is a widely used model of addiction-related behavior whose underlying mechanisms are not understood. In this study, we used dual site silicon probe recordings in [...]