Project: CRCNS Hippocampus: hc-5

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Description

Simultaneous extracellular recordings from left and right hippocampal areas CA1 and right entorhinal cortex from a rat performing a left / right alternation task and other behaviors. [about]

The data set contains recordings made using a silicon probe from three areas from a single rat that was performing different behavioral tasks.  The three regions recorded from are left and right hippocampal CA1 and right entorhinal cortex.  The tasks are a left/right alternate selection task, wheel running, and platform exploration.   The neural data was recorded on 125 channels. Included in the data set are the following items:

  • Waveforms of putative spikes extracted from original raw broadband data
  • LFPs (local field potentials)
  • Results of spike sorting
  • Information about the animal behavior during the experiment

Several publication based on some of the data:

Internally generated cell assembly sequences in the rat hippocampus. Pastalkova E, Itskov V, Amarasingham A, Buzsáki G. Science. 2008 Sep 5;321(5894):1322-7

Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop. Mizuseki K, Sirota A, Pastalkova E, Buzsáki G., Neuron. 2009 Oct 29;64(2):267-80.

Theta sequences are essential for internally generated hippocampal firing fields. Wang Y, Romani S, Lustig B, Leonardo A, Pastalkova E. Nat Neurosci. 2014 Dec 22.