The Buzsaki Lab is proud to present a large selection of experimental data available for public access. We publicly share more than a thousand sessions (about 40TB of raw and spike- and LFP-processed data) via our public data repository. The datasets are from freely moving rodents and include sleep-task-sleep sessions (3 to 24 hrs continuous recording sessions) in various brain structures, including metadata. We are happy to assist you to use these data. Our goal is that by sharing these data, other users can provide new insights, extend (or contradict/clarify) our conclusions.
The database contains electrophysiological recordings performed in freely moving rats and mice collected by investigators in the Buzsaki Lab over several years (a subset from head-fixed mice). Sessions has been collected with extracellular electrodes using high-channel-count silicon probes, with spike sorted single units, and intracellular and juxtacellular combined with extracellular electrodes. Several sessions include physiologically and optogenetically identified units. The sessions have been collected from various brain region pairs: the hippocampus, thalamus, amygdala, post-subiculum, septal region and the entorhinal cortex and various neocortical regions. In most behavioral tasks, the animals performed spatial behaviors (linear mazes and open fields), preceded and followed by long sleep sessions. Brain state classification is provided.
News
Follow our latest scientific advances, read interviews, find newly published papers, and meet the new researchers in our lab
Cocaine Place Conditioning Strengthens Location-Specific Hippocampal Coupling to the Nucleus Accumbens
Conditioned place preference (CPP) is a widely used model of addiction-related behavior whose underlying mechanisms are not understood. In this study, we used dual site silicon probe recordings in [...]
Cuba ‘sonic attack’ conspiracy theories and flawed science
Science works best when qualified people can evaluate evidence without political pressure to draw poorly founded conclusions, say 15 neuroscientists and physicists. Read the full story below or at theguardian.com [...]
Cross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation
Review article in Trends in Cognitive Sciences about our recent paper, by Alik S. Widge Transcranial electrical stimulation (TES) is a proposed tool for non-invasively modulating human brain [...]
Brain Stimulation Is All the Rage–but It May Not Stimulate the Brain
Scientific American has written a piece about our recent paper by Mihály Vöröslakos et al. looking at the effects of transcranial electric stimulation in rats and humans. You can find [...]
Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus
Memory transfer for long-term storage Explicit memory formation involves the transfer of rapidly encoded information from the hippocampus to long-term storage sites in the association cortex. Khodagholy et [...]
Pyramidal Cell-Interneuron Circuit Architecture and Dynamics in Hippocampal Networks
English, McKenzie, et al. identify, validate, and quantify monosynaptic connections between pyramidal cells and interneurons, using the spike timing of pre- and postsynaptic neurons in vivo. Their large-scale [...]