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It’s very easy to break things in biology,” said Loren Frank, a neuroscientist at the University of California, San Francisco. “It’s really hard to make them work better.” Read the full review here and see our related study below. Long-duration Hippocampal Sharp Wave Ripples Improve Memory Fernández-Ruiz A, Oliva A, Fermino de Oliveira E, Rocha-Almeida F, Tinlgey D, Buzsáki G.. Science, June 2019. [PDF] [Link] [Supplemental]
In rise of brain implants, blurring lines between man, machine? It sounds far-fetched: With a computer chip implanted in their brains, humans could boost their intelligence with instant access to the internet, write articles like this one by thinking it rather than typing, and communicate with each other without saying a thing – what entrepreneur Elon Musk calls “consensual telepathy.” Of course, it’s not really telepathy. It’s radio waves transmitting data from one [...]
News article about Antonio’s study in Scientific American by Simon Makin Specific patterns of brain activity are thought to underlie specific processes or computations important for various mental faculties, such as memory. One such “brain signal” that has received a lot of attention recently is known as a “sharp wave ripple”—a short, wave-shaped burst of high-frequency oscillations. Researchers originally identified ripples in the hippocampus, a region crucially involved in memory and [...]
The Brain from Inside Out Buzsáki, G. The Brain from Inside Out. Oxford University Press (May 2019) [Amazon] Is there a right way to study how the brain works? Following the empiricist’s tradition, the most common approach involves the study of neural reactions to stimuli presented by an experimenter. This ‘outside-in’ method fueled a generation of brain research and now must confront hidden assumptions about causation and concepts that may not hold neatly [...]
Series Combats Disorders: First Up, Epilepsy People with epilepsy were once thought to be possessed by demons or evil spirits. Dubbed “the sacred disease,” epilepsy was profoundly misunderstood for centuries, even after the disorder was explained to be of human origin. So why is it, so many years later, that epilepsy is still not fully understood? And why is there still so much stigma attached to a disorder which affects [...]
Optogenetics has rocked the world of neuroscience for more than a decade now. But neuroscientists want more from the technique—and less, including more depth and less invasiveness. As neuroscientists progress in their application of optogenetics, they want to take it further. This is evidenced by an explosion in the development of light-sensitive opsins that allow researchers to target neurons with amazing specificity. The result has been an explosion in understanding the relationships between [...]