Peter Petersen – Page 3

CellExplorer: a framework for analyzing single-cells

Peter Petersen2021-01-06T10:09:04-05:00January 6th, 2021|

CellExplorer is a graphical user interface (GUI), standardized pipeline, and data structure for exploring and classifying spike sorted single units acquired using extracellular electrodes. The large diversity of cell types of the brain provides the means by which circuits perform complex operations. Understanding such diversity is one of the key challenges of modern neuroscience. These cells have many unique electrophysiological and behavioral features from which parallel cell type classification can be inferred. CellExplorer is [...]

Happy Holidays and COVID-free 2021 to our friends

Peter Petersen2020-12-21T16:04:34-05:00December 21st, 2020|

Here is your 2021 Brain Initiative Calendar (check out September). https://braininitiative.nih.gov/sites/default/files/pdfs/2021_brain_initiative_calendar_508c.pdf

The brain is like a choir singing in an old church

Peter Petersen2020-11-26T22:09:57-05:00November 26th, 2020|

The brain is like a choir singing in an old church Svenska Dagbladet (The Swedish Daily News) published a kind review about The Brain from Inside Out. Below is the Google translation. Here is the original article in Swedish (behind paywall). And here is a PDF file of the full article in Swedish. From being perceived as a theater where the soul sits and interprets our senses, the brain has in recent years [...]

Testq

Peter Petersen2018-08-10T11:26:56-04:00August 10th, 2018|

for deletion

Transformation of a Spatial Map across the Hippocampal-Lateral Septal Circuit

Peter Petersen2018-07-10T14:09:35-04:00July 10th, 2018|

The hippocampus constructs a map of the environment. How this “cognitive map” is utilized by other brain regions to guide behavior remains unexplored. To examine how neuronal firing patterns in the hippocampus are transmitted and transformed, we recorded neurons in its principal subcortical target, the lateral septum (LS). We observed that LS neurons carry reliable spatial information in the phase of action potentials, relative to hippocampal theta oscillations, while the firing rates of LS neurons remained uninformative. Furthermore, [...]

Cocaine Place Conditioning Strengthens Location-Specific Hippocampal Coupling to the Nucleus Accumbens

Peter Petersen2018-07-09T08:43:19-04:00July 5th, 2018|

Conditioned place preference (CPP) is a widely used model of addiction-related behavior whose underlying mechanisms are not understood. In this study, we used dual site silicon probe recordings in freely moving mice to examine interactions between the hippocampus and nucleus accumbens in cocaine CPP. We found that CPP was associated with recruitment of D2-positive nucleus accumbens medium spiny neurons to fire in the cocaine-paired location, and this recruitment was driven predominantly by selective strengthening [...]