Cross-Species Neuromodulation from High-Intensity Transcranial Electrical Stimulation

2018-04-01T20:33:59-04:00March 31st, 2018|

Review article in Trends in Cognitive Sciences about our recent paper, by Alik S. Widge Transcranial electrical stimulation (TES) is a proposed tool for non-invasively modulating human brain circuits, but its ability to affect cortical physiology remains unclear. A recent study merged TES with live animal and human cadaveric recordings to verify intracranial electrical effects, then used these findings to develop a novel neuro-modulation protocol. Read the full review here and see our related [...]

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Brain Stimulation Is All the Rage–but It May Not Stimulate the Brain

2018-02-06T07:51:24-05:00February 6th, 2018|

Scientific American has written a piece about our recent paper by Mihály Vöröslakos et al. looking at the effects of transcranial electric stimulation in rats and humans. You can find their artic here and our below. Direct effects of transcranial electric stimulation on brain circuits in rats and humans. Mihály Vöröslakos, Yuichi Takeuchi, Kitti Brinyiczki, Tamás Zombori, Azahara Oliva, Antonio Fernández-Ruiz, Gábor Kozák, Zsigmond Tamás Kincses, Béla Iványi, György Buzsáki & Antal Berényi. Nature Communications 9 [...]

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Learning-enhanced coupling between ripple oscillations in association cortices and hippocampus

2017-11-01T16:20:29-04:00November 1st, 2017|

Memory transfer for long-term storage Explicit memory formation involves the transfer of rapidly encoded information from the hippocampus to long-term storage sites in the association cortex. Khodagholy et al. developed a microelectrode system for large-scale simultaneous electrophysiological monitoring of multiple sites in the rat neocortex. They observed discrete high-frequency neocortical oscillations called ripples only in the association cortex. These cortical ripples shared many properties with hippocampal ripples. Hippocampal ripples were coupled with cortical [...]

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Pyramidal Cell-Interneuron Circuit Architecture and Dynamics in Hippocampal Networks

2017-10-16T13:45:58-04:00October 16th, 2017|

English, McKenzie, et al. identify, validate, and quantify monosynaptic connections between pyramidal cells and interneurons, using the spike timing of pre- and postsynaptic neurons in vivo. Their large-scale method uncovers a backbone of connectivity rules in the hippocampus CA1 circuit. Highlights Pyramidal cell-interneuron monosynaptic connections identified using spike timing Skewed distribution of connection probability and strength Short-term plasticity of connection strength is synapse specific Presynaptic cooperativity and postsynaptic timing impact spike transmission probability [...]

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Study Finds That Rats May Have Nightmares Too

2018-04-27T19:47:45-04:00September 18th, 2017|

Nightmares may not be an experience exclusive to humans alone. New research finds that rats might have scary dreams when they fall asleep too. The study, published in Nature Neuroscience, was performed by scientists from New York University, who did an experiment that demonstrated that when rats go through frightening stages, the panic reaction they feel is reactivated during sleep. An experience perhaps similar to what some of us face [...]

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